KUALA LUMPUR, April 26 (Bernama) -- Mawi DNA Technologies (Mawi), a biotechnology company focusing on the development of innovative technologies for biosampling, announced that Prime Discoveries has successfully developed CovidDetect™, a rapid isothermal amplification diagnostic assay for detecting SARS-CoV-2.
Without the need for RNA extraction and purification, the sample result occurs in less than 30 minutes, according to a statement.
The assay uses Mawi’s new iSWAB Microbiome-EL (Extraction-Less) sample collection technology. This allows RNA release from the sample and maintains stability, protecting it from degradation and allowing room temperature storage and transport.
Chief Science Officer at Prime Discoveries, Arun Manoharan, Ph.D. said: “Our work with COVID has shown stable performance of the Mawi iSWAB Microbiome-EL for hundreds of clinical samples with similar or superior performance to RT-PCR solutions.
“Our partnership with Mawi enables Prime Discoveries to develop room temperature sampling with Extraction-Less capabilities for our rapid diagnostic solutions in many areas. These include influenza, chlamydia, gonorrhea, trichomonas, HBV, HCV, HPV, TB, herpes, syphilis, etc.
Prime Discoveries recently received CE IVD marking for CovidDetect™ and plans to pursue FDA 510K approval soon.
Clinical results from Prime CovidDetect™ have been peer reviewed and recently published in PLOS ONE under ‘A Rapid, Specific, Extraction-Less, and Cost-Effective RT-LAMP Test for the Detection of SARS-CoV-2 in Clinical Specimens’.
The CE marking allows deployment of a solution to countries in Africa and Asia where rapid, inexpensive diagnostics for various infections with minimal technical expertise and equipment infrastructure is highly required.
Prime CovidDetect™ leverages Mawi’s unique iSWAB Microbiome-EL sample collection buffer with Prime Discoveries’ patented Loop AMPlification (LAMP) technology. This allows isothermal nucleic acid amplification removing the need for expensive thermal cycling equipment required for PCR.
Founded in 2013, Mawi DNA Technologies has developed and commercialised the iSWAB technology, an innovative system for collection of biosamples.
More details at http://www.mawidna.com.
-- BERNAMA
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